Evaluation of Cardiac, Liver and Renal Indices During a Short Term Exercise Among Young Male Adults in Ado-Ekiti, Nigeria

Background and Objective: Exercise is the practice of physiological actions that maintain or improve overall wellness and physical fitness. This study was carried out to determine the effect of short-term exercise on cardiac, liver and renal indices of  young male adults in Ado-Ekiti, Ekiti State, Nigeria. Materials and Methods: A total of fifty apparently healthy male subjects aged 15-25 years who engaged in short-term jogging exercise were recruited for this study. Blood samples were collected from the subjects pre- and post-exercise. Renal and liver function parameters were estimated using a spectrophotometer, while Human Troponin I and Creatine kinase-Muscle/Brain were estimated using ELISA. Results: The results obtained showed that the CK-MB pre- and post-exercise was 7.31±0.43 and 8.53±0.71 U/L, Troponin-I was 0.41±0.17 and 0.49±0.06 ng/mL, AST was 11.41±4.02 and 11.96±4.02 U/L, ALT was 6.54±1.11 and 6.67±0.98 U/L, ALP was 136.17±39.42 and 137.62±43.89 U/L, total bilirubin was 13.13±1.83 and 13.81±1.36 µmol/L, conjugated bilirubin was 2.64±0.26 and 2.66±0.20 µmol/L, total protein was 70.06±5.21 and 70.29±5.17 g/L, albumin was 43.21±3.89 and 43.95±3.57 g/L, urea was 7.31±0.43 and 8.53±0.71 mmol/L, creatinine was 0.41±0.17 and 0.49±0.06 mmol/L, while uric acid was 0.38±0.09 and 0.43±0.12 mmol/L, respectively. Conclusion: All cardiac, liver and renal indices studied were higher in subjects post-exercise compared with pre-exercise, however only troponin-I, total bilirubin and uric acid were significantly increased. This study suggests that these parameters could be used in the assessment and monitoring of cardiac, liver and renal function among physically active exercise individuals.